Chiral Brønsted acid catalyzed enantioselective allenylation of aldehydes.
نویسنده
چکیده
A versatile and highly enantioselective chiral Brønsted acid-catalyzed allenylation of aldehydes with propargyl borolane is reported. The reaction is shown to be practical and quite general with a broad substrate scope covering aryl, heteroaryl, α,β-unsaturated, and aliphatic aldehydes.
منابع مشابه
Chiral Brønsted acid-catalyzed allylboration of aldehydes.
The catalytic enantioselective allylation of aldehydes is a long-standing problem of considerable interest to the chemical community. We disclose a new high-yielding and highly enantioselective chiral Brønsted acid-catalyzed allylboration of aldehydes. The reaction is shown to be highly general, with a broad substrate scope that covers aryl, heteroaryl, alpha,beta-unsaturated, and aliphatic ald...
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 73 شماره
صفحات -
تاریخ انتشار 2012